← Patent-cliff monitor small molecule COTELLIC COBIMETINIB FUMARATE
Loss of exclusivity December 2036 latest FDA-listed patent expiry
Company Genentech → See this company's full patent-cliff portfolio Drug detail Brand name COTELLIC Active ingredient COBIMETINIB FUMARATE Strength EQ 20MG BASE Dosage form TABLET Route ORAL Modality Small molecule FDA approval November 2015 Marketing status RX
Listed patents Patent Expires Type 11254649*PED December 2036 — 10590102*PED December 2036 — 10478400*PED December 2036 — 10590102 June 2036 substance, product 11254649 June 2036 substance, product 10478400 June 2036 substance, product 11087354*PED December 2034 — 11087354 June 2034 use U-1776 7803839*PED May 2030 — 7803839 November 2029 substance, product 8362002*PED April 2027 — 8362002 October 2026 use U-1776 11597699 October 2026 use U-3554
Regulatory exclusivity Code Expires ODE-416 October 2029 PED January 2026 M-278 July 2025
Source: FDA Orange Book, layered on the CliffBio company graph. Cliff dates are the latest FDA-listed patent expiry; estimates are projections, not legal advice.