small molecule

RYZOLT

TRAMADOL HYDROCHLORIDE

Loss of exclusivity—loss of exclusivity

CompanyPURDUE PHARMA PRODUCTS LP

Drug detail

Brand name	RYZOLT
Active ingredient	TRAMADOL HYDROCHLORIDE
Strength	200MG Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons
Dosage form	TABLET, EXTENDED RELEASE
Route	ORAL
Modality	Small molecule
FDA approval	December 2008
Marketing status	DISCN

Source: FDA Orange Book, layered on the CliffBio company graph. Cliff dates are the loss of exclusivity; estimates are projections, not legal advice.