small molecule

TWIRLA

ETHINYL ESTRADIOL; LEVONORGESTREL

Loss of exclusivityAugust 2028latest FDA-listed patent expiry

CompanyAGILE THERAPEUTICS INC

Drug detail

Brand name	TWIRLA
Active ingredient	ETHINYL ESTRADIOL; LEVONORGESTREL
Strength	0.03MG/24HR;0.12MG/24HR
Dosage form	SYSTEM
Route	TRANSDERMAL
Modality	Small molecule
FDA approval	February 2020
Marketing status	RX

Listed patents

Patent	Expires	Type
8246978	August 2028	product
8747888	July 2028	product
9050348	July 2028	product

Source: FDA Orange Book, layered on the CliffBio company graph. Cliff dates are the latest FDA-listed patent expiry; estimates are projections, not legal advice.