BENZOYL PEROXIDE; TRETINOIN
| Brand name | TWYNEO |
|---|---|
| Active ingredient | BENZOYL PEROXIDE; TRETINOIN |
| Strength | 3%;0.1% |
| Dosage form | CREAM |
| Route | TOPICAL |
| Modality | Small molecule |
| FDA approval | July 2021 |
| Marketing status | RX |
| Patent | Expires | Type |
|---|---|---|
| 12491163 | May 2041 | product |
| 12133919 | May 2041 | product |
| 12257348 | May 2041 | product |
| 12295935 | December 2040 | use U-3987 |
| 12357602 | July 2038 | product |
| 10420743 | July 2038 | use U-3194 |
| 12053546 | June 2032 | product |
| 10653899 | December 2030 | product |
| 12070629 | December 2030 | product |
| 11071878 | December 2030 | product |
| 9868103 | August 2028 | product |
| 8617580 | February 2028 | product |
| 12156946 | February 2028 | product |
Source: FDA Orange Book, layered on the CliffBio company graph. Cliff dates are the latest FDA-listed patent expiry; estimates are projections, not legal advice.