small molecule

UPNEEQ

OXYMETAZOLINE HYDROCHLORIDE

Loss of exclusivityDecember 2039latest FDA-listed patent expiry

CompanyRVL PHARMACEUTICALS INC

Drug detail

Brand name	UPNEEQ
Active ingredient	OXYMETAZOLINE HYDROCHLORIDE
Strength	0.1%
Dosage form	SOLUTION/DROPS
Route	OPHTHALMIC
Modality	Small molecule
FDA approval	July 2020
Marketing status	RX

Listed patents

Patent	Expires	Type
11103482	December 2039	product
11311515	December 2039	product
11541036	December 2039	product
11324722	December 2039	use U-2849
10940138	December 2039	use U-2849
10799481	December 2039	use U-2849
11701343	December 2039	use U-2849
12648930	December 2039	use U-2849
10898573	December 2039	product
12605363	December 2039	product
10814001	December 2039	product
8357714	August 2031	use U-2849
9867808	August 2031	use U-2849
10912765	August 2031	use U-2849

Source: FDA Orange Book, layered on the CliffBio company graph. Cliff dates are the latest FDA-listed patent expiry; estimates are projections, not legal advice.