small molecule

VYKOURA

LEUCOVORIN CALCIUM

Loss of exclusivityDecember 2044latest FDA-listed patent expiry
CompanyAVYXA HOLDINGS LLC

Drug detail

Brand nameVYKOURA
Active ingredientLEUCOVORIN CALCIUM
StrengthEQ 50MG BASE/5ML (EQ 10MG BASE/ML)
Dosage formSOLUTION
RouteINTRAMUSCULAR, INTRAVENOUS
ModalitySmall molecule
FDA approvalFebruary 2026
Marketing statusRX

Listed patents

PatentExpiresType
12564592December 2044product

Source: FDA Orange Book, layered on the CliffBio company graph. Cliff dates are the latest FDA-listed patent expiry; estimates are projections, not legal advice.

VYKOURA patent cliff — loss of exclusivity December 2044 | CliffBio