← Patent-cliff monitor Loss of exclusivity February 2034 latest FDA-listed patent expiry
Company Novartis → See this company's full patent-cliff portfolio Drug detail Brand name MEKINIST Active ingredient TRAMETINIB DIMETHYL SULFOXIDE Strength EQ 1MG **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons** Dosage form TABLET Route ORAL Modality Small molecule FDA approval May 2013 Marketing status DISCN
Listed patents Patent Expires Type 10869869*PED February 2034 — 10869869 August 2033 use U-3184 9155706*PED July 2032 — 9399021*PED July 2032 — 8580304*PED July 2032 — 9271941*PED July 2032 — 9399021 January 2032 product 8580304 January 2032 product 9155706 January 2032 product 9271941 January 2032 product 8952018*PED April 2031 — 8703781*PED April 2031 — 8952018 October 2030 use U-2020 8703781 October 2030 substance, product 7378423*PED November 2027 — 7378423 May 2027 substance, product
Regulatory exclusivity Code Expires PED September 2030 ODE-428 March 2030 PED September 2026 I-908 March 2026
Source: FDA Orange Book, layered on the CliffBio company graph. Cliff dates are the latest FDA-listed patent expiry; estimates are projections, not legal advice.